Product Details
| Product Name: Acetyl Tetrapeptide-5 | CAS No.: 820959-17-9 |
| EC-No.: 1312995-182-4 | Min. Order: 0.10000000149011612kg |
| Purity: 99% | Supply Ability: 2000kgs |
| Release date: 2026/06/29 |
| Product Name: | Acetyl Tetrapeptide-5 |
| Synonyms: | (2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid;N-Acetyl-beta-alanyl-L-histidyl-L-seryl-L-histidine;Acetyl tetrapeptide-5;Acetyl Tetrapeptide;Depuffin/Acetyl Tetrapeptide-5;Acetyl Tetrapeptide-5/eyeseryl;Depuffin;tetrapeptide |
| CAS: | 820959-17-9 |
| MF: | C20H28N8O7 |
| MW: | 492.49 |
| EINECS: | 1312995-182-4 |
| Product Categories: | BEAUTY PEPTIDES;APIs;820959-17-9 |
| Mol File: | 820959-17-9.mol |
 | |
| Acetyl Tetrapeptide-5 Chemical Properties |
| Boiling point | 1237.3±65.0 °C(Predicted) |
| density | 1.443 |
| storage temp. | 2-8°C |
| solubility | PBS (pH 7.2): 10 mg/ml |
| pka | 2.76±0.10(Predicted) |
| form | A crystalline solid |
| color | White to off-white |
| InChIKey | RIUMNDWYYDHBFO-UDJPXWLSNA-N |
| SMILES | C(O)(=O)[C@H](CC1N=CN=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1N=CN=C1)NC(=O)CCNC(C)=O |&1:3,13,19,r| |
| Acetyl Tetrapeptide-5 Usage And Synthesis |
| Chemical Properties | Acetyl Tetrapeptide-5 is a white to cream coloured powder. The active ingredient is used to treat lachrymal sacs and dark circles under the eyes. It stimulates cell metabolism, improves skin elasticity, reduces puffiness and water retention in the eye area and makes the skin supple. |
| Characteristics | Acetyl tetrapeptide-5 inhibits collagen glycation avoiding skin losing elasticity and subsequent eyebags formation . Acetyl tetrapeptide-5 prevents liquid accumulation in eyebags . Acetyl tetrapeptide-5 shows a slight lightening effect which decreases dark circles under the eyes Use level: 0.01 %, maximum 0.1 % (water soluble) |
| Uses | Acetyl tetrapeptide-5 is known as eye peptide and eye silk peptide. The molecular weight of acetyltetrapeptide-5 is 492.5 and the amino acid sequence is Ac- βAla-His-Ser-His-OH, the molecular formula is C20H28N8O7. The influence of saccharification in the body and the increase of ocular vascular osmotic pressure will make the eye skin form dark circles and edema. Some studies have proved that acetyltetrapeptide-5 can reduce edema by changing the microcirculation of regional skin and the osmotic pressure of liquid, so as to effectively eliminate edema, eye bags and dark circles. |
| Definition | Acetyl Tetrapeptide-5 is a synthetic peptide that has calming, smoothing, hydrating, and firmness-enhancing benefits when applied to skin. Its calming properties are believed to reduce undereye puffiness due to fluid accumulation, such as from allergies (which is not the same as undereye bags that occur from fat pads beneath the skin slipping out of place). |
| Application | Acetyl tetrapeptisde-5 is a known humectant or hydroscopic moisturizer which helps reduce eye puffiness, improve skin elasticity and overall smoothness. |
| benefits | Acetyl tetrapeptide-5 is an acetyl oligopeptide whose role is to inhibit collagen glycation and increase vascular permeability in a dose-dependent manner. This prevents liquid accumulation under the eyes and decreases eye puffiness, as well as improving skin elasticity. Two studies showed that acetyl tetrapeptide-5 reduced under-eye puffiness and discoloration. |
| Safety | Some humectants may be irritants at extremely high concentrations, but acetyl tetrapeptide-5 is generally considered non-hazardous to the body and the environment by the cosmetics database. |
Chongqing Zhihe Bio-pharmaceutical Co.,Ltd is mainly focus on cosmetics raw materials, our most competitive products are Phytosphingosine and has varity kinds of Ceramides, we are the the Chinese manufacturer of these.
Other two manufacturers are EVONK Germany and DOOSAN Korea, Chongqing Zhihe has the same quality with them and more competitive price.
With mature fermentation process, Zhihe can provide
ceramide NP1(IIIB),
ceramide NP2,
ceramide III,
ceramide AP(VI),
ceramide EOP,
other water souluble or oil soulble mixture of ceramides, ceramides lipidosome.
Chongqing Zhihe has R&D fermination team and Cosmetic formulation engineers team that can solve the application issues of customers.
Company Profile Introduction
Chongqing Zhihe Bio-pharmaceutical Co., Ltd. was established in August 2015, located at the foot of Jinyun Mountain, National University Science and Technology Park, Beibei District ,Chongqing, mainly engaged in the development and production of Synthetic biology technique chemical raw materials, R&D for fine chemicals technical services, Functional raw material of cosmetics, and products based on microbial fermentation biosynthesis technology (including enzyme preparations), and it is one of the major technology enterprises which are supported by Chongqing Government.
The company has established long-term and stable cooperative relationships with well-known scientific research institutions and universities at domestic and abroad, our company united academic exchanges and technical cooperation continuously, and we jointly conducted scientific research on key technologies, enhanced the company's scientific research strength, and provided a strong guarantee for the sustainable development of the company. At the same time, the company continues to invest huge amount of money in chemical raw materials, preparations, fine chemicals for technological research and development and industrial transformation. At present, the company has reserved Fusidic acid, Luriconazole, duloxetine, hyaluronic acid, L-fucose, phytosphingol, Valencia citroene and naringone and other projects with independent intellectual property rights and huge commercial value, and is carrying out industrialization and market development.
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China- Since: 2015-07-09
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