Product Details
| Product Name:
ACH-806 |
CAS No.:
870142-71-5 |
| Supply Ability:
10g |
Release date:
2026/01/05 |
Product Introduction
Bioactivity
| Name | ACH-806 |
| Description | ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM. |
| In vitro | ACH-806, an NS4A antagonist, effectively hinders the replication of the Hepatitis C Virus (HCV) with an EC50 value of 14 nM. Treatment with ACH-806 notably decreases the immunoprecipitation levels of labeled NS3 and NS4A by anti-NS3 antibody. It significantly reduces NS3 and NS4A levels and facilitates p14 formation in original replicon cells, albeit not affecting ACH-806-resistant cells[1]. Moreover, ACH-806 administration leads to notable reductions in NS3 and NS4A within transfected cells, mirroring effects observed in replicon cells treated with the compound, where both NS3 and NS4A levels decrease significantly. Following ACH-806 treatment, NS3 amounts are diminished approximately 6-fold (100/16), and NS4A-bound NS3 is reduced roughly 29-fold (261/9). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | HCVProtease | HCV Protease | HCV | GS-9132 | GS 9132 | ACH-806 | ACH806 | ACH 806 |
| Inhibitors Related | HCV-IN-30 | EIDD-1931 | Methyl 2-amino-5-bromobenzoate | RO8191 | Deferiprone | Ribavirin | Sofosbuvir | Artemisinin | HCV-IN-29 | Honokiol | (Tetrahydro-2H-pyran-4-yl)methanol | Resiquimod |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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TargetMol Chemicals Inc.
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United States