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Postion:Product Catalog >API>Hormones and the Endocrine System>Sex Hormone Drugs>ACP-105
ACP-105
  • ACP-105

ACP-105 NEW

Price $53 $83 $167
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: ACP-105 CAS No.: 899821-23-9
Purity: 99.89% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameACP-105
DescriptionACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone.
In vitroACP-105 is an orally administered, selective, and potent androgen receptor modulator (SARM), demonstrating high affinity with pEC50 values of 9.0 and 9.3 for the AR wild type and T877A mutant, respectively. In human hepatocytes, the half-life of ACP-105 (compound 1) is determined to be 5.0 hours[1].
In vivoIrradiation impaired sensorimotor function in vehicle-treated mice but not in ACP-105-treated mice. Irradiation impaired cued fear conditioning and ACP-105 enhanced fear conditioning in sham-irradiated and irradiated mice. There are relatively early radiation-induced behavioral changes in female mice and reduced MAP-2 levels in the sensorimotor cortex following ACP-105 treatment might contribute to enhanced rotorod performance[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 60 mg/mL (206.33 mM), Sonication is recommended.
Ethanol : 60 mg/mL (206.33 mM), Sonication is recommended.
KeywordsInhibitor | inhibit | AR wild type | AR T877A mutant | AndrogenReceptor | Androgen Receptor | ACP-105 | ACP105 | ACP 105
Inhibitors RelatedDehydroisoandrosterone 3-acetate | Bicalutamide | 2-Ethylhexyl trans-4-methoxycinnamate | S-23 | Enzalutamide | Octinoxate | Testosterone propionate | Allura Red AC | Sunset Yellow FCF | Ostarine | 2-sec-Butylphenol | Flutamide
Related Compound LibrariesNuclear Receptor Compound Library | Bioactive Compound Library | Anti-Prostate Cancer Compound Library | Endocrinology-Hormone Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Anti-Cancer Compound Library | Transcription Factor-Targeted Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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