AD 0261 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2025-08-22 |
Product Details
| Product Name: AD 0261 | CAS No.: 145600-69-7 |
| Supply Ability: 10g | Release date: 2025/08/22 |
Product Introduction
Bioactivity
| Name | AD 0261 |
| Description | AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions. |
| Cell Research | For measurement of [3H]TdR incorporation, cells are incubated for 16 h, and additional (6 h) incubation is carried out in the presence of [3H]TdR (0.5 μCi/well). [3H]TdR incorporation is evaluated in a liquid scintillation counter. IL-2 release from lymphocytes is estimated after 20 h incubation by enzyme immunoassay using the commercially available kits. IL-2 receptor expression is quantitated by flow cytometry using a FITC-labelled monoclonal antibody which recognizes a chain of the IL-2 receptor complex. Cell viability is determined by either the trypan blue exclusion test or propidium iodide staining. |
| In vitro | AD 0261 exhibits potent inhibitory activity on lipid peroxide generation (IC50: 0.022 μM) and superoxide anion production (IC50: 0.9-4.0 μM). It dose-dependently inhibits cytokine release/production from PHA-P-stimulated lymphocytes and all lymphocyte activation parameters, achieving 50% inhibition within 1-10 μM. AD 0261 also suppresses ornithine decarboxylase activity (IC50: ~1.0 μM). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | AD0261 | AD-0261 | AD 0261 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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