Adenosine NEW
| Price | $46 |
| Package | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Adenosine | CAS No.: 58-61-7 |
| Purity: 99.92% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Adenosine |
| Description | Adenosine (D-Adenosine) is a natural product, a ribonucleoside consisting of adenine bound to ribose. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. |
| In vitro | METHODS: Human prostate cancer cells DU-145, PC3 and LNcap-FGC-10 were treated with Adenosine (0.1-1000 μM) for 48 h. Cell viability was measured by MTT assay. RESULTS: Adenosine significantly reduced cell proliferation of DU-145, PC3 and LNcap-FGC10 cell lines in a dose-dependent manner. [1] METHODS: Human hepatocellular carcinoma cells HepG2 were treated with Adenosine (2 mM) for 6-24 h. The cell cycle was detected by Flow cytometry. RESULTS: Adenosine-induced inhibition of survival was attributed to the arrest of cell cycle progression. Adenosine significantly increased the percentage of G0/G1-phase cells and decreased the percentage of S-phase and G2/M-phase cells in HepG2 cells. [2] |
| In vivo | METHODS: To investigate the antidepressant-like effects, Adenosine (1-10 mg/kg) was intraperitoneally injected into mice and subjected to the forced swimming test (FST) and tail suspension test (TST). RESULTS: The immobilization time in the FST was shortened by intraperitoneal injection of Adenosine (5-10 mg/kg), and Adenosine (1-10 mg/kg) also produced antidepressant-like effects in the TST. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 5% DMSO+95% Saline : 1.05 mg/mL (3.93 mM), In vivo: Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. DMSO : 20 mg/mL (74.84 mM), Sonication is recommended. H2O : 2.7 mg/mL (10.1 mM), Sonication is recommended. 10% DMSO+90% Saline : 2 mg/mL (7.48 mM), In vivo: Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. |
| Keywords | vascular | regulation | platelet | NucleosideAntimetabolite | Nucleoside Antimetabolite/Analog | Nucleoside Antimetabolite | Nucleoside | neuronal | Inhibitor | inhibit | GPCR | EndogenousMetabolite | Endogenous Metabolite | endogenous | cell | blood | Autophagy | Apoptosis | Analog | aggregation | Adenosine |
| Inhibitors Related | Sucrose | Hydroxychloroquine | Daidzein | Guanidine hydrochloride | Fumaric acid | Tributyrin | Ferulic Acid | Formamide | Paeonol | Glycerol | Thymidine | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Drug Repurposing Compound Library | Miao medicine Compound Library | Microbial Natural Product Library | Tobacco Monomer Library | FDA-Approved Drug Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Gut Microbial Metabolite Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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