AE0047 Hydrochloride NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: AE0047 Hydrochloride | CAS No.: 116308-56-6 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | AE0047 Hydrochloride |
| Description | AE0047 Hydrochloride is a blocker of calcium, and used in the research of the hypertensive disease. |
| In vitro | AE0047 Hydrochloride (4e) is an antagonist of calcium[1]. AE0047 inhibits [3H]nimodipine binding to rat cardiac membrane homogenate (IC50 of 0.26 nM)[2]. AE0047 (1 μM) inhibits the high K+-evoked vascular smooth muscle contraction, and also inhibits [3H]PN200-110 binding (Ki : 40.9 nM)[3]. |
| In vivo | AE0047 (3 mg/kg) demonstrates an antihypertensive effect, reducing systolic blood pressure (ED30 of 1.1 mg/kg) [2]. In aorta isolated from stroke-prone spontaneously hypertensive rats (SHRSP), AE0047 (1 or 3 mg/25g SP diet) inhibits blood pressure elevation and enhances endothelium-dependent relaxation in response to acetylcholine [4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | CalciumChannel | Calcium Channel | AE-0047 Hydrochloride | AE0047 Hydrochloride | AE 0047 Hydrochloride |
| Inhibitors Related | Quadrol | Tricaine methanesulfonate | Nisoldipine | 2,4,6-Tri-tert-butylphenol | Chlorocresol | L-Ascorbic acid | L-Phenylalanine | L-Ascorbic acid sodium salt | 2-Nitrobenzoic acid | Magnesium Chloride Hexahydrate | Magnesium sulfate | Cinchonine |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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