AG-636 NEW
| Price | $41 | $98 | $158 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-21 |
Product Details
| Product Name: AG-636 | CAS No.: 1623416-31-8 |
| Purity: 99.19% | Supply Ability: 10g |
| Release date: 2026/04/21 |
Product Introduction
Bioactivity
| Name | AG-636 |
| Description | AG-636 is a potent, reversible, and selective DHODH inhibitor with an IC50 of 17 nM and is orally active. It demonstrates strong anticancer effects. |
| In vitro | AG-636, in cancer cell lines of hematologic versus solid tumor origin.?Differential AG-636 activity translated to the in vivo setting, with complete tumor regression observed in a lymphoma model |
| In vivo | AG-636 (10-100 mg/kg; oral gavage; twice daily; for 14 days) treatment significantly inhibits tumor growth in the OCILY19 DLBCL tumor xenograft model. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 31.25 mg/mL (91.01 mM), Sonication is recommended. 10% DMSO+90% Corn Oil : 2 mg/mL (5.82 mM), Sonication is recommended. |
| Keywords | RNASynthesis | RNA Synthesis | reversible | oral | Inhibitor | inhibit | DNASynthesis | DNA/RNA Synthesis | DNA Synthesis | Dihydroorotate Dehydrogenase | DHODH | anticancer | AG-636 | AG636 | AG 636 |
| Inhibitors Related | 5-Fluorouracil | Adenine hemisulfate | Erythromycin thiocyanate | Guanidine hydrochloride | Benzyl alcohol | 2-Methylaminoethanol | Hexane-1,6-diol | 1,4-Naphthoquinone | Adenine | Carbazole | Thymidine | Usnic Acid |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Hematonosis Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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