Pharmacodynamics 

oxygen albendazole for albendazole oxide metabolites in animal body level, is a broad-spectrum anthelmintic. A strong effect on c. elegans, tapeworms and flukes also has strong effect, its mechanism is mainly combined with nematodes tubulin play a role. Oxygen albendazole combined with B - tubulin, stop it with a - tubulin polymerization assemble into microtubules. Microtubules are many organelles, the basic structure of the unit for mitosis, assembly of protein and energy metabolism, cell reproduction is necessary. Oxalbendazole has a significantly higher affinity for nematode tubulin than mammalian tubulin and thus has little toxicity to mammals. This product not only for adult effect is strong, and larvae of immature insect body also has a strong effect, and kill the eggs, can be used for cattle, sheep of spear nematodes oster nematodes, blood, hair round worms, thin neck nematode, nematode cooper, cow back nematode, esophagus nematodes, tail nematodes and other adult and fourth stage larvae, liver piece trematode adult and moniezia, Can also be used for poultry giardia and taeniasis.

pharmacokinetic 

This product in the body metabolism into albendazole sulfone, and then metabolized to albendazole - 2 - amino sulfone, metabolites can combined with proteins. The plasma concentrations of oxalbendazole and albendazole sulfoxide in sheep after oral administration were similar to those after oral administration of albendazole, and the peak time of plasma concentrations was 8.5 hours.