Product Details
| Product Name:
AM 374 |
CAS No.:
86855-26-7 |
| Purity:
98.39% |
Supply Ability:
10g |
| Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | AM 374 |
| Description | AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM. This compound is potentially applicable in neurological disease research. |
| In vitro | AM 374 (0-9 nM) inhibits anandamide degradation in N18TG2 cells. [1] |
| In vivo | AM 374 (20 μg ; intraventricular injection, once) has no effect on lever pressing in FR5, but when used in combination with anandamide (intraperitoneal injection), it reduces lever pressing.[2] |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (6.48 mM), Sonication is recommended.
DMSO : 62.5 mg/mL (202.59 mM), Sonication is recommended.
|
| Keywords | Hexadecanesulfonyl Fluoride | FAAH | AM-374 | AM374 | AM 374 |
| Inhibitors Related | WWL 154 | Biochanin A | VU534 | 2-Chlorophenylboronic acid | N-Benzylpalmitamide | Dual FAAH/sEH-IN-1 | Carprofen | FAAH inhibitor 1 | PDP-EA | PF 750 | MM-433593 | Carmofur |
| Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | Anti-Obesity Compound Library | Inhibitor Library | Metabolism Compound Library | Lipid Metabolism Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Fluorochemical Library | Anti-Metabolism Disease Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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