AMG 579 NEW
| Price | $30 | $39 | $67 |
| Package | 1mg | 2mg | 5mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-14 |
Product Details
| Product Name: AMG 579 | CAS No.: 1227067-61-9 |
| Purity: 99.87% | Supply Ability: 10g |
| Release date: 2026/07/14 |
Product Introduction
Bioactivity
| Name | AMG 579 |
| Description | AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM). |
| In vivo | AMG 579 statistically reduces PCP-induced behavior in rats within 2 hours. In the PCP-LMA model, the minimum effective dose of AMG 579 was 0.3 mg/kg. AMG 579 has an excellent oral bioavailability of 72% in dogs[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : < 3.63 mg/mL (8.22 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.63 mg/mL (8.22 mM), Solution. DMSO : 72.5 mg/mL (164.22 mM), Sonication is recommended. |
| Keywords | Phosphodiesterase 10A | phosphodiesterase | AMG579 | AMG 579 |
| Inhibitors Related | Balipodect | Theophylline monohydrate | D(+)-Raffinose pentahydrate | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Sildenafil citrate | Doxofylline |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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