Product Details
| Product Name:
Anipamil |
CAS No.:
83200-10-6 |
| Supply Ability:
10g |
Release date:
2026/07/15 |
Product Introduction
Bioactivity
| Name | Anipamil |
| Description | Anipamil is a long-acting blocker of calcium channel,and for the treatment of cardiovascular disease. |
| In vivo | Anipamil effectively suppresses the proliferation of smooth muscle cells (SMC), promoting a more differentiated phenotype characterized by the expression of smooth muscle myosin heavy chain (SM-MyHC) compared to untreated controls. In 2K-1C rabbits, oral administration of anipamil (40 mg) significantly reduces or eliminates intimal thickening and decreases the presence of immature SMC types in the media layer. Furthermore, renal function protection is notably enhanced in anipamil (2 mg/kg/day)-treated groups compared with those receiving hydralazine, achieving equivalent blood pressure management. Anipamil also demonstrates efficacy in arrhythmic assays, specifically reducing ventricular tachycardia (VT) at doses of 1.0 mg/kg + 0.10 mg/kg/min or 5.0 mg/kg + 0.50 mg/kg/min, although ventricular fibrillation (VF) remains unaffected. In rats undergoing substantial nephrectomy (five-sixths removed) and treated with anipamil (0.5 mg/kg/day, orally), outcomes are improved, showing lower mortality, better-managed mean arterial blood pressure, and reduced serum creatinine levels compared to controls. |
| Storage | Keep away from direct sunlight,Keep away from moisture,
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Anipamil |
| Inhibitors Related | Quadrol | Tricaine methanesulfonate | Nisoldipine | 2,4,6-Tri-tert-butylphenol | Chlorocresol | L-Ascorbic acid | L-Phenylalanine | L-Ascorbic acid sodium salt | 2-Nitrobenzoic acid | Magnesium Chloride Hexahydrate | Magnesium sulfate | Cinchonine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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