Antalarmin NEW
| Price | $453 | $613 | $828 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-21 |
Product Details
| Product Name: Antalarmin | CAS No.: 157284-96-3 |
| Purity: 99.99% | Supply Ability: 10g |
| Release date: 2026/04/21 |
Product Introduction
Bioactivity
| Name | Antalarmin |
| Description | Antalarmin is a selective and potent corticotropin-releasing factor receptor 1 (CRHR1) antagonist that crosses the blood-brain barrier and blocks CRF activation and carrageenan-induced subcutaneous inflammation in rats. |
| In vitro | Antalarmin (100 nM; 48 hours) treatment was able to block CRF-induced increases in PKAIIβ levels in hippocampal neurons derived from Tg2576 mice[2]. |
| In vivo | In the chronic mild stress model using BALB/cByJIco male mice, intraperitoneal administration of Antalarmin (10 mg/kg; once daily for 4 weeks) was able to significantly improve the physical state of the mice[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 20 mg/mL (52.83 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 2 mg/mL (5.28 mM), Sonication is recommended. |
| Keywords | CRHR1 |
| Inhibitors Related | Urotensin I acetate (83930-33-0 Free base) | Crinecerfont | Astressin acetate | (R)-Crinecerfont | Tildacerfont | CP 376395 | CP 316311 | Tetracosactide acetate | NBI-27914 | Corticotropin-releasing factor (human) acetate | CRF (6-33) acetate(120066-38-8 free base) | K 41498 aceate |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Human Metabolite Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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| $48.00 |
VIP6Y
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TargetMol Chemicals Inc.
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2026-06-02 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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