Antitubercular agent-27 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Antitubercular agent-27 | CAS No.: 2460651-09-4 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Antitubercular agent-27 |
| Description | Antitubercular agent-27 (compound 1) exhibits potent antitubercular properties with an IC50 of 3.2 μM, an MIC of 7.8 μM, and an IC90 of 7.0 μM, effectively targeting resistant Mycobacterium tuberculosis H37Rv isolates and displaying significant intracellular antimycobacterial activity with low cytotoxicity [1]. |
| In vitro | Antitubercular agent-27 (compound 1) exhibits significant antimycobacterial activity against resistant isolates of M. tuberculosis H37Rv with IC50 values of 2.4, 100, 120, 1.3, and 3.1 μM, MICs of 3.2, 140, 160, 2.4, and 4.2 μM, and IC90 values of 3.0, 120, 142, 2.2, and 3.5 μM for FQ-R1, INH-R1, INH-R2, RIF-R1, and RIF-R2, respectively [1]. Additionally, it shows antibacterial activity with MIC values of 0.80 μM (low oxygen) and 0.45 μM (normal oxygen), IC50 values of 0.23 μM (low oxygen) and 0.27 μM (normal oxygen), and IC90 values of 0.43 μM (low oxygen) and 0.35 μM (normal oxygen) [1]. The compound also demonstrates intracellular activity with an IC50 of 1.45 μM and IC90 of 1.61 μM, and exhibits low cytotoxicity with an IC50 of >100 μM [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $269.00 |
VIP4Y
|
TargetMol Chemicals Inc.
|
2026-05-11 | |
| $34.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-05-11 | |
|
Shanghai Yimeixin Technology Co., LTD
|
2026-06-23 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
INQUIRY