Arctiin NEW
| Price | $30 | $42 | $54 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: Arctiin | CAS No.: 20362-31-6 |
| Purity: 98.47% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | Arctiin |
| Description | Arctiin (Arctigenin-4-glucoside) acts on an agonists of the adiponectin receptor 1 with anti-cancer effects. |
| Cell Research | HaCaT cells are plated at 1×105 cells in 25-mm-diameter dishes. Twenty-four hours after plating, various concentrations of arctiin are added to the culture medium. From the first to the third day after plating, the number of viable cells is counted by the trypan blue dye exclusion test.(Only for Reference) |
| In vitro | Arctiin induces growth inhibition and dephosphorylates the tumor-suppressor retinoblastoma protein in human immortalized keratinocyte HaCaT cells. The growth inhibition caused by arctiin is associated with the downregulation of cyclin D1 protein expression. The arctiin-induced suppression of cyclin D1 protein expression occurs in various types of human tumor cells, including osteosarcoma, lung, colorectal, cervical and breast cancer, melanoma, transformed renal cells and prostate cancer[1]. |
| In vivo | Arctiin has anti-cancer properties in animal models. arctiin has a remarkable anti-tumor-promoting effect as seen in a two-stage carcinogenesis test of mouse skin tumors induced by 7,12-dimethylbenz[α]anthracene(DMBA) as an initiator and 12-Otetradecanoyl phorbol-13-acetate (TPA) as a promoter by topical and oral administration. It also has a protective effect on 2-amino-1-methyl-6- phenylimidazo[4,5-β]pyridine (PhIP)-induced carcinogenesis particularly in the mammary gland during the promotion period[1]. Arctiin is orally effective against either IFV-inoculated normal or 5-fluorouracil (5-FU)-treated mice[3]. |
| Storage | Keep away from moisture,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 10 mg/mL (18.71 mM), Solution. H2O : 3.18 mg/mL (5.95 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.74 mM), Sonication is recommended. Ethanol : 93 mg/mL (173.98 mM), Sonication is recommended. DMSO : 247.5 mg/mL (463.01 mM), Sonication is recommended. |
| Keywords | NSC-315527 | NSC315527 | Arctiin | Adiponectinreceptor | Adiponectin receptor |
| Inhibitors Related | Undecane | Sodium propionate | Ethyl palmitate | Kojic acid | Uridine | Fumaric acid | 1,4-Naphthoquinone | Glucosamine | Ethyl linoleate | D-Psicose | N,N-Dimethylacetamide | Magnesium sulfate |
| Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Miao medicine Compound Library | Natural Product Library | Saccharide and Glycoside Natural Product Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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