Arecoline NEW
| Price | $40 | $92 |
| Package | 100mg | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: Arecoline | CAS No.: 63-75-2 |
| Purity: 98.00% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | Arecoline |
| Description | Arecoline is a natural alkaloid derived from areca nut in the palm family and is a potent nicotine and partial agonist of muscarinic acetylcholine receptors. Arecoline has anti-anxiety and anti-parasitic activity, can induce oxidative stress and can be used to study Alzheimer's disease and Alzheimer's disease. |
| In vitro | Arecoline induces reactive oxygen species generation and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting p21/Cip1 expression. It also upregulates stress-responsive genes such as hemeoxygenase-1, ferritin light chain, glucose-6-phosphate dehydrogenase, glutamate-cysteine ligase catalytic subunit, and glutathione reductase. At higher concentrations, arecoline causes epithelial cell death due to oxidative trauma without triggering apoptosis[1]. |
| Storage | Keep away from direct sunlight,Keep away from moisture,Store under nitrogen Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 10 mg/mL (64.44 mM), Solution. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (12.89 mM), Sonication is recommended. DMSO : 250 mg/mL (1610.93 mM), Sonication is recommended. H2O : 200 mg/mL (1288.74 mM), Sonication and heating are recommended. |
| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | Nicotinic Receptor | AChR |
| Inhibitors Related | Ethoxyquin | Cysteamine hydrochloride | Imeglimin hydrochloride | Acetylcysteine | Urethane | L-Ascorbic acid | Adenine | L-Cystine | (-)-Epigallocatechin Gallate | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | N,N-Dicyclohexylcarbodiimide |
| Related Compound Libraries | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Alkaloid Natural Product Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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