Argatroban NEW
| Price | $33 | $54 | $105 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-15 |
Product Details
| Product Name: Argatroban | CAS No.: 74863-84-6 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2026/07/15 |
Product Introduction
Bioactivity
| Name | Argatroban |
| Description | Argatroban is a specific thrombin inhibitor and a non-heparin anticoagulant that effectively prevents thrombus formation and is commonly used to establish thrombolysis models. |
| In vitro | In a rat distal cerebral artery occlusion model, administration of Argatroban at a dose of 0.3 mg/hour significantly reduced the number of microthrombi following artery occlusion. Argatroban treatment (at 0.1 and 0.3 mg/hour) notably reversed the decline in local cerebral blood flow in rats with distal cerebral artery occlusion. |
| In vivo | Argatroban directly induces phenotypic transformation in vascular smooth muscle cells, upregulating the expression of myofilament-related proteins, PAI-1, and β-actin mRNA. In animal models with thrombosis rich in platelets and erythrocytes, Argatroban (ED50=125 μg/kg) demonstrates antithrombotic effects. It exhibits antithrombin activity across a range (Ki=5 nM-39 nM). |
| Storage | Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.93 mM), Sonication is recommended. Ethanol : 6 mg/mL (11.8 mM), Sonication is recommended. DMSO : 247.5 mg/mL (486.6 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Thrombin | MD805 | MD 805 | MCI9038 | MCI 9038 | Inhibitor | inhibit | Argatroban |
| Inhibitors Related | Dabigatran Etexilate Mesylate | (S)-(+)-Ibuprofen | Edoxaban | AEBSF hydrochloride | Heparin sodium salt | Ozagrel | Avatrombopag | Dabigatran etexilate | Argatroban Monohydrate | Eltrombopag Olamine | Anisindione | p-Hydroxycinnamic acid |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Approved Drug Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | NMPA-Approved Drug Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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