Product Details
| Product Name:
Asp-AMS |
CAS No.:
828288-98-8 |
| Supply Ability:
10g |
Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | Asp-AMS |
| Description | Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor. |
| In vitro | Asp-AMS is a 500-fold stronger competitive inhibitor of the mitochondrial enzyme than aspartol-AMP (10 nM) and a 35-fold weaker competitor of human and bovine cyt-AspRSs (300 nM). It exhibits the highest inhibitory effect on the mitochondrial enzyme and is the most active inhibitor with Ki values in the nanomolar range, having a stronger effect on bacterial AspRSs (E. coli and P. aeruginosa) than on human cytosolic AspRS. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 3.3 mg/mL (7.15 mM), Sonication is recommended.
DMSO : 100 mg/mL (216.73 mM), Sonication is recommended.
|
| Keywords | Aspartyl-tRNA synthetase, Mitochondrial enzyme | Asp-AMS | AspAMS | Asp AMS |
| Inhibitors Related | Ciprofloxacin hydrochloride monohydrate | 1-Hexanol | Imeglimin hydrochloride | Rotenone | Glibenclamide | Permethrin | Ciprofloxacin monohydrochloride | (-)-Epigallocatechin Gallate | Phosphocreatine disodium | Sodium Molybdate | 4-Pentenoic acid | L-Histidine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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