AZD-0284 NEW
| Price | $37 | $96 | $146 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: AZD-0284 | CAS No.: 2101291-07-8 |
| Purity: 99.82% | Supply Ability: 10g |
| Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | AZD-0284 |
| Description | AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1]. |
| In vitro | AZD0284 (0.37 μM; 5 days) inhibits IL-17A production in human TH17 cells[1], reduces polarization of TH17 into pathogenic TH17/1 cells, decreases the frequency of IL-17+ cells and double positive TH17/1 cells, and reduces IL-17A secretion and RNA expression of IL-17A, IL-17F, IL-22, and IL-23R[1][2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 1 mg/mL (1.91 mM), Sonication is recommended. DMSO : 99 mg/mL (188.78 mM), Sonication is recommended. |
| Keywords | vulgaris | tract | TH17 | RORγ | ROR | respiratory | RAR-related orphan receptor | psoriasis | production | plaque | L-23R | Inhibitor | inhibit | IL-22 | IL-17F | IL-17A | cells | AZD-0284 | AZD0284 | AZD 0284 |
| Inhibitors Related | S18-000003 | T0901317 | GSK2981278 | GSK805 | MRL-871 | Nobiletin | XY101 | Melatonin | SR2211 | SR 1903 | Cholesterol | ML 209 |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | ReFRAME Related Library | Kinase Inhibitor Library | Multi-Target Compound Library | Drug Repurposing Compound Library | Post-Translational Modification Compound Library | Metabolism Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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