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Postion:Product Catalog >AZD3229
AZD3229
  • AZD3229

AZD3229 NEW

Price $37 $89 $143
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: AZD3229 CAS No.: 2248003-60-1
Purity: 99.46% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameAZD3229
DescriptionAZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. It demonstrates potent single-digit nM growth inhibition across a broad cell panel.
In vivoFollowing a single dose (AZD3229, 20 mg/kg), high free cover over the target is achieved and is associated with complete suppression of pKIT and downstream markers out to 8 hours. As the compound is cleared and cover declines, these signals recover although recovery is not complete even at 24 hours.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Saline : < 3.13 mg/mL (6.53 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
H2O : Insoluble
DMSO : 31.25 mg/mL (65.17 mM), Sonication is recommended.
10% DMSO+90% Corn Oil : 5 mg/mL (10.43 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.13 mg/mL (6.53 mM), Solution.
KeywordsSCFR | Kit | Inhibitor | inhibit | c-Kit | cKit | CD117 | AZD-3229 | AZD3229 | AZD 3229
Inhibitors RelatedGilteritinib | Regorafenib monohydrate | Sunitinib | Toceranib Phosphate | Sorafenib | Dasatinib | Pexidartinib | Regorafenib | Lenvatinib mesylate | Dasatinib monohydrate | Lenvatinib | Pazopanib
Related Compound LibrariesAnti-Lung Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Hematonosis Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Preclinical Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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