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Postion:Product Catalog >Organic Chemistry>Hydrocarbons and derivatives>Cyclic hydrocarbons>AZD4573
AZD4573
  • AZD4573

AZD4573 NEW

Price $59 $165 $243
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-06

Product Details

Product Name: AZD4573 CAS No.: 2057509-72-3
Purity: 99.63% Supply Ability: 10g
Release date: 2026/05/06

Product Introduction

Bioactivity

NameAZD4573
DescriptionAZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
In vitroShort-term administration of AZD4573 induced a swift, dose- and time-dependent reduction in cellular pSer2-RNAPII levels, which in turn activated caspase 3, leading to apoptosis across a wide spectrum of hematological cancer cell lines. Notably, caspase activation exhibited an EC50 of 13.7 nM in the acute myeloid leukemia model MV4-11.
In vivoAZD4573 demonstrates a short half-life (<1 hour) in multiple species (dog, rat, monkey) and possesses good solubility for intravenous administration.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (9.3 mM), Sonication is recommended.
DMSO : 118.75 mg/mL (276.2 mM), Sonication is recommended.
KeywordsInhibitor | inhibit | Cyclin dependent kinase | CDK9 | CDK | AZD-4573 | AZD4573 | AZD 4573
Inhibitors RelatedRibociclib | (E)-β-Farnesene | Amantadine | 2-Chloropyrazine | Kojic acid | Abemaciclib | 2,4,6-Trihydroxybenzoic acid | Palbociclib | Abemaciclib methanesulfonate | Sodium Oxamate | Seliciclib | Dinaciclib
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$59.00
VIP6Y
TargetMol Chemicals Inc.
2026-05-06

TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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