Azelastine hydrochloride NEW
| Price | $45 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Azelastine hydrochloride | CAS No.: 79307-93-0 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Azelastine hydrochloride |
| Description | Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity. |
| In vivo | In the rat basophilic leukemia RBL-2H3 cell line, Azelastine inhibited antigen (Ag)-induced TNF-alpha release (IC50=25.7 mM) and ionomycin-induced TNF-alpha release (IC50=1.66 mM). In mouse peritoneal macrophages, Azelastine suppressed inducible nitric oxide synthase (iNOS) mRNA expression and nitric oxide (NO) production. In normal human mast cells, Azelastine inhibited the secretion of IL-6, TNF-alpha, and IL-8, and the activation of NF-κB, as well as intracellular calcium levels. In human gingival fibroblasts, Azelastine dose-dependently inhibited DNA and protein synthesis. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 84 mg/mL (200.78 mM), Sonication is recommended. H2O : 35 mg/mL (83.66 mM), Sonication is recommended. Ethanol : 57 mg/mL (136.25 mM), Sonication is recommended. |
| Keywords | SARS-CoV | SARSCoV | SARS coronavirus | Inhibitor | inhibit | HistamineReceptor | Histamine Receptor | H1 receptor | Azelastine Hydrochloride | Azelastine hydrochloride | Azelastine | asthma | antihistamine | allergic rhinitis |
| Inhibitors Related | EIDD-1931 | Meclizine dihydrochloride | Remdesivir | Silymarin | Lidocaine | Molnupiravir | Hydroxychloroquine | Famotidine | Chloroquine phosphate | Sodium butanoate | Dexamethasone | Alginic acid |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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