Manufacturer Provide GMP Aztreonam CAS 78110-38-0 Strength Materials 99% Aztreonam Lysine

Introduction

Product Name: Aztreonam Lysine

Other Name : Aztreonam L-Arginine;(E)-2-(((1-(2-aminothiazol-4-yl)-2-((2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino)-2-oxoethylidene)amino)oxy)-2-methylpropanoic acid;Aztreonam/arginine

CAS NO:78110-38-0

Purity: 99%min
Appearance:White Powder

Molecular formula: C13H17N5O8S2

MW:435.43

Melting Point :227°C

Density :1.83 g/cm3(Predicted)

Solubility :Soluble in DMF/water (1:1) at 50 mg/ml

Storage :Sealed in dry,Store in room temp

Aztreonam has the characteristics of weak immunogenicity and less cross allergy with penicillins and cephalosporins, so it can be used to replace aminoglycoside drugs to treat aerobic gram-negative bacterial infections in patients with renal impairment; Under observation, it is used for patients allergic to penicillin and cephalosporin.

Application & function

1. Urinary tract infections: simple and complex pyelonephritis caused by Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella odorifera, Citrobacter, Serratia marcescens And recurrent cystitis.

2. Lower respiratory tract infections: Pneumonia and bronchitis caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter and Serratia marcescens.

3. Bloodstream infections: bloodstream infections caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Serratia marcescens and Enterobacter.

4. Skin and soft tissue infections: skin and soft tissue infections (including surgical wound infections) caused by Escherichia coli, Proteus mirabilis, Serratia marcescens, Enterobacter, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Citrobacter , Ulcer and burn wound infection).

5. Peritonitis and other abdominal infections: including Escherichia coli, Klebsiella smelly nose, Klebsiella pneumoniae, Enterobacter cloacae, Pseudomonas aeruginosa, Citrobacter, and Serratia marcescens. Often need to be combined with anti-anaerobic drugs such as metronidazole.

6. Reproductive tract infections: Gynecological infections such as Escherichia coli, Klebsiella pneumoniae, Enterobacter (including Enterobacter cloacae), Pseudomonas aeruginosa, Proteus mirabilis, such as endometritis, pelvic inflammatory disease, etc. Need to be combined with anti-anaerobic drugs such as metronidazole