Bafilomycin B1 NEW
| Price | $70 |
| Package | 100μg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Bafilomycin B1 | CAS No.: 88899-56-3 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Bafilomycin B1 |
| Description | Bafilomycin B1 is a macrolide antibiotic discovered in Streptomyces gresuis. It exhibits neuroprotective effects and V-ATPase inhibitory activity, and can also inhibit LDL-induced lipid droplet accumulation. |
| In vitro | Bafilomycin B1 (1 nM, 24 h) significantly suppressed chloroquine-induced death in cerebellar granule neurons[1]. Bafilomycin B1 (0.1-10 nM, 48 h) did not induce cell death or apoptosis in SH-SY5Y cells at concentrations ≤ 1 nM, and significantly attenuated chloroquine-induced cell death when 50 μM chloroquine was added [2]. Bafilomycin B1 (10–40 nM, 37°C) significantly inhibited surface binding, intracellular accumulation, and degradation of oxidized 125I-LDL in J774 cells [3]. |
| In vivo | In homozygous nematodes overexpressing human wild-type α-synuclein in dopaminergic neurons, Bafilomycin B1 (50–150 μg/mL, 24 hours) provided significant protection against α-synuclein-induced dopaminergic degeneration [2]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80.00 mg/mL (98.04 mM), Sonication is recommended. |
| Keywords | Bafilomycin B-1 | Bafilomycin B1 |
| Inhibitors Related | Neomycin sulfate | Ampicillin sodium | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Metronidazole | Doxycycline | Penicillin G sodium salt | Penicillin G potassium | EDTA copper(II) disodium salt | Ethyl acetoacetate | Ampicillin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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