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Postion:Product Catalog >Natural Products>Iridoid derivatives>Barlerin
Barlerin
  • Barlerin

Barlerin NEW

Price $34 $48 $77
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-04-20

Product Details

Product Name: Barlerin CAS No.: 57420-46-9
Purity: 99.83% Supply Ability: 10g
Release date: 2026/04/20

Product Introduction

Bioactivity

NameBarlerin
DescriptionBarlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ elevation and caspase-3 activity, and improvement of mitochondrial energy metabolism.8-O-Acetylshanzhiside methylester can increase angiogenesis and improve functional recovery after stroke.8-O-Acetylshanzhiside methylester has protective effects on experimental myocardial ischemia injury, the effects might be due to block of myocardial inflammatory cascades through an HMGB1-dependent NF-κB signaling pathway.8-O-Acetylshanzhiside methylester protects diabetic brain against I/R injury by alleviating diabetic cerebral I/R injury and attenuating blood–brain barrier (BBB) breakdown, and its protective effects may involve HMGB-1 and NF-κB signalling pathway.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 82 mg/mL (182.86 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (7.36 mM), Sonication is recommended.
KeywordsVEGFR | TNF-α | Nuclear factor-κB | Nuclear factor-kappaB | NF-Κb | NFκB | NF-kB | NFkB | ND-01 | ND 01 | Inhibitor | inhibit | Caspase | Barlerin | Akt
Inhibitors RelatedKaolin | Aceglutamide | Gum arabic | Kojic acid | Hyaluronic acid | 1,8-Cineole | 1,4-Naphthoquinone | Tributyrin | Ethyl linoleate | D-Psicose | Magnesium acetate tetrahydrate | N,N-Dimethylacetamide
Related Compound LibrariesAnti-Tumor Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Selected Plant-Sourced Compound Library | Natural Product Library | Saccharide and Glycoside Natural Product Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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