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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Beclabuvir
Beclabuvir
  • Beclabuvir

Beclabuvir NEW

Price $137
Package 1mg
Supply Ability: 10g
Update Time: 2026-07-27

Product Details

Product Name: Beclabuvir CAS No.: 958002-33-0
Purity: 99.93% Supply Ability: 10g
Release date: 2026/07/27

Product Introduction

Bioactivity

NameBeclabuvir
DescriptionBeclabuvir is an allosteric inhibitor that binds to thumb site 1 of the HCV NS5B RNA-dependent RNA polymerase, inhibiting recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 (IC50 < 28 nM).
In vitro2- or 3-drug combinations of beraprevir with pegIFN/RBV and with a range of DAAs (e.g., HCV NS5A inhibitors, NS3 protease inhibitors, and/or nucleoside analog NS5B inhibitors) can show additive or synergistic antiviral activity [2].
In vivoThe combination of Beclabuvir with daclatasvir and asunaprevir achieves very high rates of viral eradication (about 90%) in patients infected with HCV genotype 1, which is the most common genotype worldwide [1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.03 mM), Sonication is recommended.
DMSO : 20 mg/mL (30.31 mM), Sonication is recommended.
KeywordsNS5B protein | HCVProtease | HCV Protease | HCV NS5A | BMS791325 | BMS 791325 | Beclabuvir
Inhibitors RelatedEIDD-1931 | Methyl 2-amino-5-bromobenzoate | RO8191 | Sofosbuvir | Ribavirin | Deferiprone | Artemisinin | HCV-IN-29 | Honokiol | Chlorcyclizine | (Tetrahydro-2H-pyran-4-yl)methanol | Resiquimod

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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