Berberine chloride NEW
| Price | $30 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-05-15 |
Product Details
| Product Name: Berberine chloride | CAS No.: 633-65-8 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2026/05/15 |
Product Introduction
Bioactivity
| Name | Berberine chloride |
| Description | Berberine chloride (Natural Yellow 18) is an alkaloid derived from Hydrastis canadensis L. of the Berberidaceae family, serving as a commonly used intestinal antibacterial agent. Berberine chloride exhibits biological activities including anti-inflammatory, hypoglycemic, lipid-regulating, antitumor, and cardiovascular protective effects. Berberine chloride can be utilized in research on chronic diseases and tumors. |
| In vitro | Methods: Copper complexes (0–100 μM), berberine chloride (0–100 μM), and a combination treatment (copper complexes (0–100 μM) + BBC (50 μM)) were added to MDA-MB-231 VIM RFP (triple-negative breast cancer cells) and MCF-10A (normal human mammary epithelial cells). Incubation time: 24, 48, 72 h; cell viability was assessed using the CCK-8 assay. Results: Berberine chloride significantly inhibited cell growth, and combination therapy significantly enhanced cytotoxicity against cancer cells. [1] Methods: LoVo cells were treated with 40 μM berberine chloride for 24 h, and cell cycle distribution was analyzed by flow cytometry. Results: Berberine chloride induced G?/M phase arrest in LoVo cells. [2] |
| In vivo | Methods: Using a LoVo cell xenograft model in nude mice, Berberine chloride was administered orally at doses of 10, 30, and 50 mg/kg for 10 consecutive days, and the tumor suppression rate was calculated. Results: The tumor suppression rate for 50 mg/kg Berberine chloride reached 45.3%, with no significant toxicity observed in mouse body weight or spleen.[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 21.00 mg/mL (56.48 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) H2O : < 1 mg/mL (insoluble or slightly soluble) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1.00 mg/mL (2.69 mM), Sonication is recommended. |
| Keywords | Topoisomerase | ReactiveOxygenSpecies | Reactive Oxygen Species | Natural Yellow-18 | Natural Yellow18 | Inhibitor | inhibit | Berberine Hydrochloride | Berberine Chloride | Berberine | Bacterial | Autophagy | Antibiotic |
| Inhibitors Related | Sucrose | Neomycin sulfate | Aceglutamide | Hemin | D(+)-Raffinose pentahydrate | Ethyl linoleate | Malic acid | Glycerol | Thymidine | Dimethyl sulfoxide | Gluconate Calcium | Sodium bicarbonate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Alkaloid Natural Product Library | Drug Repurposing Compound Library | Natural Product Library | Anti-Viral Compound Library | Antiparasitic Natural Product Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bitter Compound library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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