Product Details
| Product Name:
Bexlosteride |
CAS No.:
148905-78-6 |
| Supply Ability:
10g |
Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | Bexlosteride |
| Description | Bexlosteride (LY300502), a benzoquinolinone derivative, functions as a human type I 5α-reductase inhibitor. It demonstrates metabolic inhibition, antiproliferative, and antisecretory activities specifically in LNCaP human prostatic adenocarcinoma cell cultures, positioning it as a potent agent for prostate cancer research [1] [2]. |
| In vitro | Bexlosteride effectively inhibits the reductive metabolism of [3 H-T] in LNCaP cells in a concentration-dependent manner, displaying an IC 50 of 5.77 nM[1]. At concentrations above 10 nM, it significantly counteracts the Testosterone-induced promotion of LNCaP cellular proliferation and completely inhibits Testosterone's mitogenic effects on these cells at 1000 nM[1]. Furthermore, Bexlosteride markedly opposes Testosterone-induced PSA secretion at concentrations of 30 nM or higher[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Bexlosteride |
| Inhibitors Related | FH1 | Furaneol | Epalrestat | Quercitrin hydrate | Dicoumarol | 4-hydroxyphenyl acetate | Lapisteride | Alpha-Estradiol | Finasteride | Isoliquiritigenin | AKR1C1-IN-1 | Kopexil |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
-
-
CAS:1779524-90-1
$1520.00
-
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
|
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States