BI-4464 NEW
| Price | $31 | $74 | $118 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: BI-4464 | CAS No.: 1227948-02-8 |
| Purity: 99.81% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | BI-4464 |
| Description | BI-4464 is a highly selective inhibitor targeting focal adhesion kinase (FAK). BI-4464 effectively blocks the catalytic activity of FAK by competitively binding to the ATP-binding site, with an IC?? of 17 nM. In addition to its role as a kinase inhibitor, BI-4464 can also serve as a FAK-targeting ligand (warhead) for PROTAC design. By conjugation with an E3 ligase ligand via an appropriate linker, the resulting PROTAC molecule can induce the selective degradation of FAK through the ubiquitin–proteasome pathway, providing a valuable tool for cancer biology and related disease research. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 16.67 mg/mL (30.01 mM), Sonication is recommended. |
| Keywords | Target Protein-binding Moiety | PTK2/FAK | PTK2 protein tyrosine kinase 2 | PTK2 | LigandsforTargetProteinforPROTAC | Ligands for Target Protein for PROTAC | Inhibitor | inhibit | Focal adhesion kinase | FAK | BI-4464 | BI4464 | BI 4464 |
| Inhibitors Related | Chloropyramine hydrochloride | (+)-JQ-1 | CPI-0610 carboxylic acid | Ibrutinib | Ifebemtinib FA | Ifebemtinib | OXA-11 | Creosol | Y15 | PND-1186 | Dasatinib carbaldehyde | Quizartinib |
| Related Compound Libraries | Highly Selective Inhibitor Library | Bioactive Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Multi-Target Compound Library | Angiogenesis related Compound Library | Post-Translational Modification Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Cytoskeletal Signaling Pathway Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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