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Postion:Product Catalog >BIBB 515
BIBB 515
  • BIBB 515

BIBB 515 NEW

Price $40 $89 $135
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: BIBB 515 CAS No.: 156635-05-1
Purity: 99.68% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameBIBB 515
DescriptionBIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of animal, plant, and fungal sterols. OSC catalyzes the conversion of (3S)-2, 3-oxidosqualene to lanosterol, a precursor to cholesterol, in mammals and fungi. Total cholesterol was reduced by 19% in normolipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic hamsters at a dose of 148 mg/kg/day for 25 days.
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationEthanol : 0.15 mg/mL (0.39 mM), Sonication is recommended.
DMSO : 2 mg/mL (5.25 mM), Sonication is recommended.
Keywordssterol | Oxidosqualene cyclase | OSC | metabolism | lipid-lowering | LDL | Inhibitor | inhibit | effect | cyclase | cholesterol | BIBB-515 | BIBB515 | BIBB 515 | 2,3-oxidosqualene
Inhibitors RelatedPCSK9-IN-11 | Pirozadil | 2-Acetamidophenol | 20-HC-Me-Pyrrolidine | Propane-1,2,3-triyl tripalmitate | LDL-IN-3 | PCSK9-IN-10 | Moxonidine | Nicanartine | 1,2-Cyclohexanedione | Pep 2-8 ammonium salt(1541011-97-5 free base) | Muvalaplin
Related Compound LibrariesBioactive Compound Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | Lipid Metabolism Compound Library | Orally Active Compound Library | Clinical Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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