Biperiden Hydrochloride NEW
| Price | $129 | $423 |
| Package | 10mg | 50mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-20 |
Product Details
| Product Name: Biperiden Hydrochloride | CAS No.: 1235-82-1 |
| Purity: 99.70% | Supply Ability: 10g |
| Release date: 2026/04/20 |
Product Introduction
Bioactivity
| Name | Biperiden Hydrochloride |
| Description | Biperiden Hydrochloride (KL 373 Hydrochloride) is an anticholinergic antiparkinsonian agent that selectively blocks central M1 cholinoreceptors while exerting atropine-like effects on peripheral parasympathetic structures. Biperiden Hydrochloride is approved for the adjunctive treatment of postencephalitic, idiopathic, and arteriosclerotic Parkinson’s disease, demonstrates minimal impairment of novelty preference compared with other anticholinergics in comparative cognitive studies, and is associated with known adverse effects including drowsiness, vertigo, headache, and dizziness. |
| In vitro | In human pancreatic ductal adenocarcinoma cell lines (Panc-1, Panc-2, and BxPC3), treatment with Biperiden Hydrochloride (29.6 μg/mL) for 72 hours inhibited cell proliferation and induced apoptosis [1]. |
| In vivo | In a subcutaneous xenograft mouse model using Panc-1 pancreatic cancer cells, intraperitoneal administration of Biperiden Hydrochloride (10 mg/kg, Daily) for 3 weeks resulted in an 83% reduction in tumor size via MALT1 inhibition [4]. Separately, in a pilocarpine-induced epilepsy model, Biperiden treatment (8 mg/kg, i.p., every 8 hours) for 10 days modified the progression of epileptogenesis. It reduced the frequency of spontaneous recurrent seizures and lowered extracellular glutamate levels in the hippocampus, leading to a long-term decrease in hippocampal excitability [5]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2.6 mg/mL (7.47 mM), Sonication is recommended. H2O : 5 mg/mL (14.37 mM), Sonication is recommended. |
| Keywords | KL-373 | KL373 | KL 373 (Hydrochloride) | KL 373 | Biperiden Hydrochloride |
| Inhibitors Related | Adiphenine hydrochloride | Levamisole hydrochloride | Ethyl (triphenylphosphoranylidene) acetate | Urethane | Hexamethonium Bromide | Ribavirin | Adenine | Mitotane | Choline chloride | Propoxur | N,N-Dicyclohexylcarbodiimide | Arecoline |
| Related Compound Libraries | Approved Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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