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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>BIX-01294
BIX-01294
  • BIX-01294

BIX-01294 NEW

Price $34 $77 $119
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: BIX-01294 CAS No.: 935693-62-2
Purity: 99.64% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameBIX-01294
DescriptionBIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
Cell ResearchOn the first day, cells were seeded in 96 well plates.?Twenty-four hours later, BIX-01294 was added at the indicated concentrations in each well.?After treatment by BIX-01294 for another 24 h, we used 10% TCA to immobilize the cells and then evaluated the living cell numbers using the sulforhodamine B assay as previously described[1]
In vitroBIX-01294 induced caspase-dependent apoptosis in human bladder cancer cells.?BIX-01294 stimulates endoplasmic reticulum stress (ER stress) and up-regulated expression of PMAIP1 through DDIT3 up-regulation.?Furthermore, down-regulation of the deubiquitinase USP9X by BIX-01294 results in downstream reduction of MCL1 expression, leading to apoptosis eventually[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 84.17 mg/mL (171.55 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (6.73 mM), Sonication is recommended.
KeywordsSUV39H1(H320R) | recurrent | PRMT1 | p53 | p21 | MLKL | Inhibitor | inhibit | HistoneMethyltransferase | Histone Methyltransferase | H3K9me3 | H3K9me2 | Gadd45a | G9a | Cdkn1a | BIX-01294 | BIX01294 | BIX 01294 | Autophagy
Inhibitors RelatedStavudine | Aceglutamide | Hemin | Tamoxifen | Cysteamine hydrochloride | Guanidine hydrochloride | Hydroxychloroquine | Enzalutamide | Paeonol | Naringin | Alginic acid | Sildenafil citrate
Related Compound LibrariesMethylation Compound Library | Reprogramming Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Chromatin Modification Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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