Product Details
| Product Name:
Blebbistatin |
CAS No.:
674289-55-5 |
| Purity:
99.88% |
Supply Ability:
10g |
| Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | Blebbistatin |
| Description | Blebbistatin ((±)-Blebbistatin) is a non-muscle myosin II (NMII)-selective and non-muscle myosin heavy chain 9 (MYH9)-specific inhibitor that promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing, while preserving the integrity of cell junctions and barrier function. |
| In vitro | Blebbistatin is a cell-permeable non-muscle myosin II ATPases inhibitor with an IC50 range of 2 μM. |
| In vivo | METHODS: Blebbistatin ((±)-Blebbistatin) (10, 20, 40 mg/kg, intraperitoneal injection, once every two days, 4 weeks) was administered to NCl-H460 model nude mice, and the changes in tumors in the mice were observed.
RESULTS The inhibition rates of Blebbistatin ((±)-Blebbistatin) on xenograft tumor weight were 23.4%, 40.2%, and 83.4%, respectively. [1] |
| Storage | Store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 23 mg/mL (78.68 mM), Sonication is recommended.
|
| Keywords | non-muscle myosin II ATPases | Myosin | Inhibitor | inhibit | Blebbistatin |
| Inhibitors Related | Mavacamten | Sodium oleate | Permethrin | Tolbutamide | trans-Aconitic acid | Phlorizin | Chlorpropamide | 2,3-Butanedione 2-Monoxime | 4-Hydroxyacetophenone | Revaprazan hydrochloride | Oleic acid | Cyclocreatine |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Multi-Target Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:1217619-62-9
$1660.00
-
-
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1520.00
|
VIP2Y
|
TargetMol Chemicals Inc.
|
2026-04-20 |
United States