BMS-303141 NEW
| Price | $39 | $61 | $79 |
| Package | 2mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: BMS-303141 | CAS No.: 943962-47-8 |
| Purity: 99.47% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | BMS-303141 |
| Description | BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL). |
| In vitro | BMS-303141 shows inhibition of total lipid syntheses with an IC50 of 8 μM in HepG2 cells. BMS-303141 shows no cytotoxicity up to 50 lM under a cell-based Alamar Blue cytotoxicity assay, indicating the observed inhibition of lipid synthesis is not a result of compound-induced cytotoxicity[1]. |
| In vivo | Chronic oral administration of BMS-303141 to mice on a high-fat diet reduces plasma cholesterol and triglycerides by approximately 20-30% and fasting plasma glucose by 30-50%. Continued treatment with BMS-303141 gradually inhibits weight gain and decreases adiposity without affecting food consumption. BMS-303141 displays an oral bioavailability of 55% and a relatively brief half-life of 2.1 hours[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 247.5 mg/mL (583.31 mM), Sonication is recommended. |
| Keywords | Inhibitor | inhibit | BMS-303141 | BMS303141 | ATPCitrateLyase | ATP Citrate Lyase | ACLY | ACL |
| Inhibitors Related | SB 204990 | Forrestiacids J | ACLY Inhibitor 7 | Hydroxycitric acid tripotassium hydrate | (-)-Hydroxycitric acid lactone | MEDICA16 | EVT0185 | 2-Furoic acid | Bempedoic acid | NDI-091143 | Citric acid trilithium salt tetrahydrate | (-)-Hydroxycitric acid |
| Related Compound Libraries | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Inhibitor Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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