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Postion:Product Catalog >BMS-906024
BMS-906024
  • BMS-906024

BMS-906024 NEW

Price $545 $1200 $1990
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: BMS-906024 CAS No.: 1401066-79-2
Purity: 99.88% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameBMS-906024
DescriptionBMS-906024 (Osugacestat) is an orally available and selective inhibitor of γ-secretase, a small molecule Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity against a variety of human cancer xenografts.BMS-906024 prevents the activation of all four Notch receptors, and is active against Notch1, -2, -3 and -4 receptors. BMS-906024 prevents the activation of all four Notch receptors, with IC50s of 1.6, 0.7, 3.4 and 2.9 nM for Notch1, -2, -3 and -4 receptors, respectively.
In vitroBMS-906024 (100 nM; 72 h) is an effective Notch activation inhibitor, which enhances the in vitro anti-tumor activity of paclitaxel[1].
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 5 mg/mL (8.98 mM), Sonication is recommended.
Keywordsγ secretase | Notch4 | Notch3 | Notch2 | Notch1 | Notch | Gammasecretase | BMS-906024 | BMS906024 | BMS 906024
Inhibitors RelatedValproic acid sodium salt | Aβ42-IN-2 | Sulindac sulfide | Tangeretin | gamma-secretase modulator 1 | Valproic Acid | Nirogacestat | Hexamethylene bisacetamide | CB-103 | Prednisone acetate | Carvacrol | RO7185876
Related Compound LibrariesAnti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Cancer Cell Differentiation Compound Library | Hematonosis Compound Library | Drug Repurposing Compound Library | Stem Cell Differentiation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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