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Postion:Product Catalog >API>Antibiotics>Other antibiotic Drugs>Borrelidin
Borrelidin
  • Borrelidin

Borrelidin NEW

Price $278
Package 1mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: Borrelidin CAS No.: 7184-60-3
Purity: 98.00% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameBorrelidin
DescriptionBorrelidin (Treponemycin) is a nitrogen-containing macrolide antibiotic isolated from Streptomyces rochei, which inhibits sugar-acyl-tRNA synthetase. It exhibits anticancer, antifungal, and anti-angiogenesis activities, inhibiting tumor growth and lung metastasis.
In vitroBorrelidin can effectively inhibit the proliferation of ALL cell lines with a maximum 50% inhibitory concentration of 50 ng/mL. [1] The 50% inhibitory concentration (IC50) of Borrelidin for Cdc28/Cln2 was 24 μM. Borrelidin is a potent angiogenesis inhibitor with an IC50 value of 0.8 nM that induces apoptosis in angioforming cells. [3] Borrelidin showed highly selective cytotoxicity to cancer cells and endothelial cell subpopulations. [4]
In vivoBorrelidin (0.25 mg/kg intraperitoneally injected) in combination with fumagilin increased antimalarial activity in Plasmodium berghei-infected mice. [5]
StorageStore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationEthanol : 100 mg/mL (204.23 mM), Sonication is recommended.
KeywordsCdc28/Cln2 | Borrelidin
Inhibitors RelatedNeomycin sulfate | Stavudine | Aceglutamide | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Hydroxychloroquine | 2-Amino-2-methyl-1-propanol | Doxycycline | Fenpyroximate | Formamide | Alginic acid

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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