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Postion:Product Catalog >BPC 157
BPC 157
  • BPC 157

BPC 157 NEW

Price Get Latest Price
Package 1box 10box 100box
Min. Order: 1box
Supply Ability: 20tons
Update Time: 2026-06-01

Product Details

Product Name: BPC 157 Min. Order: 1box
Purity: 99% Supply Ability: 20tons
Release date: 2026/06/01

 BPC 157 Product Introduction

Overview BPC 157 (Body Protection Compound?157) is a synthetic, stable gastric pentadecapeptide composed of 15 amino acids with the sequence Gly?Glu?Pro?Pro?Pro?Gly?Lys?Pro?Ala?Asp?Asp?Ala?Gly?Leu?Val (GEPPPGKPADDAGLV). It is derived from a protective protein in human gastric juice and is widely used in preclinical research for its potential wound?healing, gastrointestinal cytoprotective, and neuroprotective activities. Identifiers: CAS 137525?51?0; molecular formula C62H98N16O22; average molecular weight ≈1419.5 Da. Suppliers typically offer it as a white to off?white lyophilized powder intended for research use only61012.

Reported Key Features and Mechanisms

Gastrointestinal mucosal protection and ulcer healing: demonstrates cytoprotection in the GI tract and cultured enteric neurons/glia. In ex vivo organ bath studies using rat and human intestinal strips, BPC 157 at 40 μmol/L suppressed motility; ELISA showed reduced 5?hydroxytryptamine (5?HT) in rat ileum and colon, suggesting modulation of enteric 5?HT synthesis/release.

Modulation of catecholaminergic and dopaminergic pathways: in a 48?h restraint?stress GI lesion model in rodents, protection by BPC 157 (intragastric or intraperitoneal, 10 μg or 10 ng/kg) was abolished by co?administration of phentolamine, clonidine, or haloperidol, but not by prazosin, yohimbine, or domperidone; atenolol blocked only intraperitoneal protection, while propranolol affected only intragastric protection. Co?stimulation with adrenaline and bromocriptine markedly reduced lesion development.

Vasomotor and endothelial function: reported to modulate vascular tone via thec–Caveolin?1–endothelial nitric oxide synthase (eNOS)** pathway in preclinical studies.

Toxicology and safety signals: animal studies report a favorable safety profile; however, human clinical data are limited, and it is not approved for clinical use in major regulatory regions (e.g., US/EU)



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