BPH-1358 free base NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-21 |
Product Details
| Product Name: BPH-1358 free base | CAS No.: 801985-13-7 |
| Supply Ability: 10g | Release date: 2026/04/21 |
Product Introduction
Bioactivity
| Name | BPH-1358 free base |
| Description | BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL). |
| In vitro | BPH-1358 is the most potent inhibitor of both E. coli UPPS (EcUPPS) and S. aureus UPPS (SaUPPS) with an IC50 of 110 nM and EC50s of 300 nM and 290 nM, respectively, against E. coli and S. aureus [1]. |
| In vivo | In an i.p. infection model with an MRSA strain, BPH-1358 is active against S. aureus (20/20 mice survived) [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | NSC-50460 | NSC50460 | NSC 50460 | human bisphosphonate farnesyl diphosphate synthase | BPH-1358 free base | BPH1358 free base | BPH-1358 | BPH1358 | BPH 1358 free base | BPH 1358 |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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