Bromoenol lactone NEW
| Price | $94 | $147 |
| Package | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-26 |
Product Details
| Product Name: Bromoenol lactone | CAS No.: 88070-98-8 |
| Purity: 99.98% | Supply Ability: 10g |
| Release date: 2026/05/26 |
Product Introduction
Bioactivity
| Name | Bromoenol lactone |
| Description | Bromoenol lactone ((6E)-Bromoenol lactone) is a selective calcium-dependent phospholipase A2?(iPLA2β) and serine protease inhibitor that attenuates nicotine-induced breast cancer cell proliferation and migration, inhibits voltage-gated Ca2+ and transient receptor potential classical channels, and inhibits carrageenan-induced prostaglandin production and hyperalgesia in rat hind paws. |
| In vitro | Bromoenol lactone inhibits exocytosis when stimulated using a Ca2+ ionophore A23187, which passively transports Ca2+ down a concentration gradient and also in permeabilised mast cells where Ca2+ entry is no longer relevant. In RBL 2H3 and bone marrow-derived mast cells (BMMCs), Ca2+ entry is critical for exocytosis. Moreover, Bromoenol lactone has only a minor effect on antigen- or thapsigargin-stimulated Ca2+ signalling, both the release from internal stores and sustained elevation due to Ca2+ influx. [1] |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 40 mg/mL (126.11 mM), Sonication is recommended. |
| Keywords | PLA2 | Bromoenol lactone |
| Inhibitors Related | Neomycin sulfate | Levamisole hydrochloride | 1-Naphthaleneacetic acid potassium salt | Difluprednate | trans-Benzylideneacetone | Benzylideneacetone | Omeprazole | Indomethacin | Darapladib | 1-Naphthaleneacetic acid | Lansoprazole | Magnesium sulfate |
| Related Compound Libraries | Bioactive Compound Library | Protease Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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