BSH-IN-1 NEW
| Price | $118 | $297 | Get Latest Price |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-28 |
Product Details
| Product Name: BSH-IN-1 | CAS No.: 2553217-91-5 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2026/05/28 |
Product Introduction
Bioactivity
| Name | BSH-IN-1 |
| Description | BSH-IN-1 is a potent, covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM for B. longum BSH and 427 nM for B. theta BSH). |
| In vitro | BSH-IN-1 also inhibits BSH activity in growing cultures of Gram-negative (Bacteroides fragilis ATCC 25285, B. theta VPI-5482, and Bacteroides vulgatus ATCC 8482) and Gram-positive (C. perfringens ATCC 13124, Lactobacillus plantarum WCFS1, and Bifidobacterium adolescentis L2–32) bacteria. BSH-IN-1 also is a potent BSH inhibitor in growing bacterial cultures with IC50s of 237 nM and 1070 nM for B. adolescentis and B. theta, respectively. |
| In vivo | In C57BL/6 mice, BSH-IN-1 (10?mg/kg; a single dose; gavage）inhibits BSH activity and can be gut-restricted. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 40 mg/mL (97.9 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.89 mM), Sonication is recommended. |
| Keywords | PotassiumChannel | Potassium Channel | BSH-IN-1 | BSHIN1 | BSH IN 1 | Bile salt hydrolase (BSH) |
| Inhibitors Related | Neomycin sulfate | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Cesium chloride | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Bioactive Lipid Compound Library | Potassium Channel Targeted Library | Fluorochemical Library | Ion Channel Targeted Library | Anti-Cancer Compound Library | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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