BTT-3033 NEW
| Price | $108 | $158 | $266 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: BTT-3033 | CAS No.: 1259028-99-3 |
| Purity: 99.36% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | BTT-3033 |
| Description | BTT-3033 is an orally active and potent α2β1 (EC50: 130 nM) inhibitor with an affinity for the α2I domain, inhibiting platelet binding to collagen I and cell proliferation. BTT-3033 induces apoptosis and can be used to study prostate cancer, inflammation, and cardiovascular disease. |
| In vitro | BTT-3033 and BTT-3034 inhibited cell adhesion to rat tail collagen I with EC50 values of 130 and 160 nM, respectively, and corresponding Emax values of 97 and 86% .Neither BTT-3033 nor BTT-3034 (at EC50 concentrations) inhibited the adhesion of MG-63 cells to vitronectin, 120-kDa fibronectin or 40-kDa fibronectin, assays that measured αV, α5β1, and α4β1 integrin function, respectively [2]. |
| In vivo | Integrin α2β1 function blocking sulfonamides BTT-3016, BTT-3033(oral administration, 10 mg/kg) and BTT-3034 have anti-inflammatory effects in PAF-stimulated air pouch model[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Corn oil : 10 mg/mL (21.48 mM), Solution. 10% DMSO+90% (20% SBE-β-CD in Saline) : < 10 mg/mL (21.48 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. 10% DMSO+90% Saline : < 10 mg/mL (21.48 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 140 mg/mL (300.75 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : < 10 mg/mL (21.48 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| Keywords | α2β1 integrin | BTT-3033 | Apoptosis |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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