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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>BTZ043
BTZ043
  • BTZ043

BTZ043 NEW

Price $38 $59 $118
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: BTZ043 CAS No.: 1161233-85-7
Purity: 99.97% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameBTZ043
DescriptionBTZ043 is a DprE1 inhibitor with nanomolar bactericidal activity against Mycobacterium tuberculosis in vitro.
In vitroThe inhibition of BTZ-resistant DprE1 followed the trend observed in the MIC measurements, with the C387 g mutant being more resistant to inhibition by PyrBTZ01, PyrBTZ02, and BTZ043 (7- to 9-fold increases in IC50) than the C387S mutant (2.5- to 4-fold increases in IC50).
In vivoBTZ-043 was administered at 100 mg/kg (b.i.d., p.o.), and sulfamethoxazole/trimethoprim (SXT), at 100 mg/kg sulfamethoxazole, was used as a positive control.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Corn Oil : 1.5 mg/mL (3.48 mM), Sonication is recommended.
10% DMSO+90% Saline : < 1.56 mg/mL (3.62 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1.56 mg/mL (3.62 mM), Solution.
DMSO : 15.6 mg/mL (36.16 mM), Sonication is recommended.
10% DMSO+90% Corn oil : < 1.56 mg/mL (3.62 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+90% (20% SBE-β-CD in Saline) : < 1.56 mg/mL (3.62 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
Keywordstuberculosis | Inhibitor | inhibit | DprE1 | BTZ-043 | BTZ043 | BTZ 043 | Bacterial | Antibiotic
Inhibitors RelatedNeomycin sulfate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate | BES
Related Compound LibrariesTarget-Focused Phenotypic Screening Library | Bioactive Compound Library | ReFRAME Related Library | Antibiotics Library | Drug Repurposing Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Bacterial Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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