Product Details
| Product Name:
Butabindide |
CAS No.:
175553-48-7 |
| Supply Ability:
10g |
Release date:
2026/05/11 |
Product Introduction
Bioactivity
| Name | Butabindide |
| Description | Butabindide (UCL-1397) is a potent, selective inhibitor of tripeptidyl peptidase II (TPP II), with Ki values of 10 μM and 7 nM for TPP I and TPP II, respectively, inhibiting TPP II to protect CCK-8 against inactivation [1] [2]. |
| In vitro | Butabindide (also known as UCL-1397; concentration range: 0-24 nM; applied to rat cerebral cortex membranes) effectively inhibits tripeptidyl-peptidase II (TPP II) activity in cerebral membranes. |
| In vivo | Butabindide (UCL-1397; 10 mg/kg; i.v.; for 20 min) effectively inhibits the degradation of CCK-8 within the gastrointestinal tract, enhancing satiety in mice [2]. Using a mouse model (25-30 g), intravenous administration of the compound at 10 mg/kg over 20 minutes reduced food intake and induced satiation behaviors. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Inhibitors Related | PMSF | AEBSF hydrochloride | Imidazole | Subtilisin | p-Aminobenzamidine dihydrochloride | Chymotrypsin | Proteinase K | Aprotinin | Ac-Ala-OH | Trypsin | FOY 251 | Benzamidine hydrochloride |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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