CA-170 NEW
| Price | $2820 | $3480 | $4400 |
| Package | 25mg | 50mg | 100mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-22 |
Product Details
| Product Name: CA-170 | CAS No.: 1673534-76-3 |
| Supply Ability: 10g | Release date: 2026/05/22 |
Product Introduction
Bioactivity
| Name | CA-170 |
| Description | CA-170 is an orally bioavailable dual inhibitor of VISTA and PD-L1 that selectively restores T-cell proliferation and effector function suppressed by immune checkpoint signaling, while demonstrating minimal off-target activity across a broad receptor and enzyme panel, making CA-170 a valuable compound for immuno-oncology research and immune checkpoint modulation studies. |
| In vitro | PD-1 is a co-receptor that is expressed predominantly by T cells. The binding of PD-1 to its ligands, PD-L1 or PD-L2, is important for the physiological regulation of the immune system[1]. |
| In vivo | In preclinical studies using syngeneic mouse tumor models (e.g., colorectal cancer and melanoma), oral administration of CA-170 inhibits tumor growth [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 24 mg/mL (66.61 mM), Sonication is recommended. |
| Keywords | PD-1 | CA-170 |
| Inhibitors Related | LSD1-IN-24 | PD-1/PD-L1-IN-9 | BMS-1166-n-piperidine-co-n-piperazine dihydrochloride | IMMH 010 maleate | Icariside I | Fraxinellone | Pembrolizumab | LSD1-IN-27 | Acesulfame Potassium | Anti-Mouse PD-1 Antibody (RMP1-14) | Panaxadiol | JQ-1 (carboxylic acid) |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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