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Postion:Product Catalog >Analytical Chemistry>Analysis reagents>General Analytical Reagents>Calcimycin
Calcimycin
  • Calcimycin

Calcimycin NEW

Price $69
Package 1mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: Calcimycin CAS No.: 52665-69-7
Purity: 98.00% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

NameCalcimycin
DescriptionCalcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes, uncouples oxidative phosphorylation, and inhibits ATPase of rat liver mitochondria. The substance is primarily used as a biochemical tool to study the role of divalent cations in various biological systems.
In vitroCalcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner [4].
In vivoCalcimycin (2.5 or 7.5 nM; intrapleurally) induces protein leakage [5].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.82 mM), Sonication is recommended.
DMSO : 47 mg/mL (89.76 mM), Sonication is recommended.
Keywordsphosphorylation | mycobacterial | ionophore | Inhibitor | inhibit | Gram-positive | Fungal | divalent | cation | Calcimycin | Bacterial | bacteria | Autophagy | Apoptosis | Antifungal | Antibiotic A23187 | Antibiotic A 23187 | Antibiotic | A23187 | A 23187
Inhibitors RelatedNeomycin sulfate | Calcium Propionate | Aceglutamide | Hemin | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Sulfamethoxazole sodium | Formamide | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

Product name Price   Suppliers Update time
$69.00
VIP6Y
TargetMol Chemicals Inc.
2026-05-11

TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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