Calcimycin NEW
| Price | $69 |
| Package | 1mg |
| Supply Ability: | 10g |
| Update Time: | 2026-08-08 |
Product Details
| Product Name: Calcimycin | CAS No.: 52665-69-7 |
| Purity: 98.00% | Supply Ability: 10g |
| Release date: 2026/08/08 |
Product Introduction
Bioactivity
| Name | Calcimycin |
| Description | Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes, uncouples oxidative phosphorylation, and inhibits ATPase of rat liver mitochondria. The substance is primarily used as a biochemical tool to study the role of divalent cations in various biological systems. |
| In vitro | Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner [4]. |
| In vivo | Calcimycin (2.5 or 7.5 nM; intrapleurally) induces protein leakage [5]. |
| Storage | Store at low temperature,Keep away from direct sunlight,Store under nitrogen,Keep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.82 mM), Sonication is recommended. DMSO : 47 mg/mL (89.76 mM), Sonication is recommended. |
| Keywords | phosphorylation | mycobacterial | ionophore | Inhibitor | inhibit | Gram-positive | Fungal | divalent | cation | Calcimycin | Bacterial | bacteria | Autophagy | Apoptosis | Antifungal | Antibiotic A23187 | Antibiotic A 23187 | Antibiotic | A23187 | A 23187 |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Aceglutamide | Hemin | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Sulfamethoxazole sodium | Formamide | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $69.00 |
VIP6Y
|
TargetMol Chemicals Inc.
|
2026-08-08 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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