Calicheamicin NEW
| Price | $228 | $572 | $822 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Calicheamicin | CAS No.: 108212-75-5 |
| Purity: 98.85% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Calicheamicin |
| Description | Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks. |
| In vitro | PF-06647263 (anti-EFNA4-ADC) is generated by conjugating hE22 lysine residues to the AcButDMH-N-Ac-calicheamicin-γ1 linker-payload, with an average drug-to-antibody ratio (DAR) of 4.6. PF-06647263 induces antigen- and concentration-dependent cytotoxicity, causing cell death after 96 hours of exposure (EC50: ~1 ng/mL) [1]. |
| Storage | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 100 mg/mL (73.08 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (2.92 mM), Sonication is recommended. |
| Keywords | Calicheamicins | Calicheamicin γ-1 | Calicheamicin γ 1 | Calicheamicin r1 | Calicheamicin gamma1 | Calicheamicin | ADCCytotoxin | ADC Cytotoxin |
| Inhibitors Related | Neomycin sulfate | Aceglutamide | Levulinic acid | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Formamide | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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