Carbimazole NEW
| Price | $29 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: Carbimazole | CAS No.: 22232-54-8 |
| Purity: 99.98% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | Carbimazole |
| Description | Carbimazole (Athyromazole) is an Imidazolium thyroid antagonist, which is rapidly transformed into MMI in vivo and can be converted into methidazole in vitro, and can be used in the study of Graves' disease. |
| Kinase Assay | In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. Total and phosphorylated S6 at ser235/236 and ser240/244 are detected by western analysis using phosphospecific antibodies. Note that recombinant GST-tagged S6 (53 kd) is distinguished from endogenous S6 (32 kd) on the western blot. |
| In vivo | Once absorbed by the human body, Carbimazole is metabolized into Methimazole, which exerts anti-thyroid activity. It specifically targets conditions such as hyperthyroidism (excessive production of thyroid hormones) and thyrotoxicosis (thyroid inflammation). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (10.74 mM), Sonication is recommended. Ethanol : 12 mg/mL (64.44 mM), Sonication is recommended. DMSO : 60 mg/mL (322.18 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Thyroidhormonereceptor(THR) | Thyroidhormonereceptor | Thyroid peroxidase | Thyroid hormone receptor(THR) | Thyroid hormone receptor | THR | MMI | methimazole | Inhibitor | inhibit | Graves' disease | Carbimazole | antithyroid agent |
| Inhibitors Related | Undecane | Esculin | Bisphenol A | Semaglutide | Fumaric acid | (Rac)-Hesperetin | D-Psicose | Skatole | SB 202190 | Afatinib | FERULIC ACID METHYL ESTER | Nisin Z |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Kinase Inhibitor Library | Drug Repurposing Compound Library | Drug-Fragment Library | NO PAINS Compound Library | FDA-Approved Kinase Inhibitor Library | Anti-Cancer Approved Drug Library | Bitter Compound library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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