Carprofen NEW
| Price | $36 | $52 | $75 |
| Package | 50mg | 100mg | 200mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-11 |
Product Details
| Product Name: Carprofen | CAS No.: 53716-49-7 |
| Purity: 99.65% | Supply Ability: 10g |
| Release date: 2026/06/11 |
Product Introduction
Bioactivity
| Name | Carprofen |
| Description | Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. |
| In vitro | Administration of 4 mg/kg Carprofen significantly elevated peak plasma concentrations in dogs. Compared to buprenorphine, Carprofen treatment resulted in marginally superior analgesic effects with reduced sedative action in canines. Preoperative administration of Carprofen in dogs yielded lower pain scores than other groups, with marked effectiveness observed 2 hours post-extubation. Carprofen provided sustained analgesia for 18 hours in treated canines without adverse side effects and notably improved the speed of recovery in limping birds. |
| In vivo | Carprofen binds to human serum albumin (HSA) via fluorescence and equilibrium dialysis methods, with two sets of binding constants [K1=5.1 μM (fluorescence) and 3.7 μM (ED), K2=37 μM (fluorescence) and 13 μM (ED)]. It predominantly binds to site II, the benzodiazepine site, while site I, the Warfarin site, exhibits a lower affinity for Carprofen. The carboxyl group of Carprofen plays a significant role in its high-affinity binding with HSA. Additionally, Carprofen (S and R enantiomers) inhibits canine COX2 with an IC50 of 0.102 microM, primarily attributed to the S enantiomer (IC50, 0.0371 μM), which is approximately 200 times more potent than the R enantiomer (IC50, 5.97 microM). |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 123 mg/mL (449.38 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (14.61 mM), Sonication is recommended. Ethanol : 51 mg/mL (186.33 mM), Sonication is recommended. |
| Keywords | Fatty acid amide hydrolase | FAAH | COX-2 | COX | Carprofen | Autophagy |
| Inhibitors Related | Sucrose | Aceglutamide | Hemin | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Glycerol | Thymidine | Trometamol | Gluconate Calcium | DL-Lysine |
| Related Compound Libraries | Highly Selective Inhibitor Library | Pain-Related Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | High Solubility Fragment Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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