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Postion:Product Catalog >CDDO-dhTFEA
CDDO-dhTFEA
  • CDDO-dhTFEA

CDDO-dhTFEA NEW

Price $64 $93 $155
Package 1mg 2mg 5mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: CDDO-dhTFEA CAS No.: 1191265-33-4
Purity: 99.59% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameCDDO-dhTFEA
DescriptionCDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-κB and transforming growth factor-β pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).
In vivoCDDO-dhTFEA restores hypertension, increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis, and inflammation in the chronic kidney disease rats [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (17.4 mM), Suspension.
DMSO : 250 mg/mL (434.99 mM), Sonication is recommended.
10% DMSO+90% Saline : < 10 mg/mL (17.4 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
KeywordsRTA dh-404 | RTA dh404 | RTA dh 404 | Nuclear factor-κB | Nuclear factor-kappaB | Nrf2 | NF-κB | NFκB | NF-kB | NFkB | Keap1-Nrf2 | Inhibitor | inhibit | CDDO-dhTFEA | CDDOdhTFEA | CDDO dhTFEA
Inhibitors RelatedStavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Ethyl linoleate | D-Psicose | Formamide | Dimethyl phthalate | Alginic acid | Sildenafil citrate
Related Compound LibrariesFerroptosis Compound Library | Bioactive Compound Library | Anti-Ovarian Cancer Compound Library | Antioxidant Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Anti-Cancer Active Compound Library | Anti-Hypertension Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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