Ceftiofur hydrochloride NEW
| Price | $39 |
| Package | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2026-04-22 |
Product Details
| Product Name: Ceftiofur hydrochloride | CAS No.: 103980-44-5 |
| Purity: 99.12% | Supply Ability: 10g |
| Release date: 2026/04/22 |
Product Introduction
Bioactivity
| Name | Ceftiofur hydrochloride |
| Description | Ceftiofur hydrochloride (U-67279A) is the hydrochloride salt form of ceftiofur, a semisynthetic, beta-lactamase-stable, broad-spectrum, third-generation cephalosporin with antibacterial activity. |
| In vitro | Ceftiofur can downregulate tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and interleukin-6 (IL-6), but did not affect interleukin-10 (IL-10) production. Ceftiofur significantly inhibits extracellular signal-regulated kinase (ERK), p38, and c-jun NH(2)-terminal kinase (JNK) phosphorylation protein expression in RAW 264.7 cells. Ceftiofur also inhibits p65-NF-kappaB translocation into the nucleus in RAW 264.7 cells. [1] |
| In vivo | Ceftiofur treatment is associated with a significant decrease in rectal temperature and diarrhea in neonatal calves. Ceftiofur results in a significant decrease in fecal shedding of Salmonella organisms in neonatal calves. [2] Ceftiofur hydrochloride (intrauterine (i.u.)) reduces the prevalence of positive uterineculture in cows with clinical endometritis (29.0 vs. 51.4%) and reduces the overall prevalence of Arcanobacterium pyogenes (1.0 vs. 7.6%) at 51 d in milk (DIM) . Ceftiofur hydrochloride reduces the prevalence of uterine infection in cows with clinical endometritis, and the prevalence of A. pyogenes, but does not affect the prevalence of subclinical endometritis or fertility of dairy cows already receiving PGF(2alpha). [3] Ceftiofur hydrochloride (i.m. injection) results in C(max) of 11.8 mg/mL at 1-4 hours after injection, the mean area under the curve (AUC) of 216 m g x h/mL in pigs. [4] Ceftiofur hydrochloride (2.2 mg of CE/kg, SC or IM, once daily for 5 days) is efficacious for treatment of acute postpartum metritis (APM) in dairy cows. [5] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 21 mg/mL (37.5 mM), Sonication is recommended. DMSO : 93 mg/mL (166.07 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Inhibitor | inhibit | Excenel Hydrochloride | Ceftiofur Hydrochloride | Ceftiofur | Bacterial | Antibiotic | Antibacterial |
| Inhibitors Related | Neomycin sulfate | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Hydroxypropyl Cellulose | Ethyl linoleate | D-Psicose | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Gluconate Calcium | Sodium diacetate | Sodium bicarbonate |
| Related Compound Libraries | Bioactive Compound Library | Anti-Bacterial Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36 Washington Street, Wellesley Hill, MA
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