Product Details
| Product Name:
CH7057288 |
CAS No.:
2095616-82-1 |
| Purity:
99.92% |
Supply Ability:
10g |
| Release date:
2026/04/21 |
Product Introduction
Bioactivity
| Name | CH7057288 |
| Description | CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively. |
| In vitro | CH7057288, a potent and selective TRK inhibitor belonging to a novel chemical class.CH7057288 induced regression of intracranial tumors and greatly improved event-free survival in an intracranial implantation model mimicking brain metastasis. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 34 mg/mL (59.68 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.51 mM), Sonication is recommended.
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| Keywords | Tropomyosin related kinase receptor | Trkreceptor | Trk receptor | Trk | Inhibitor | inhibit | CH-7057288 | CH7057288 | CH 7057288 |
| Inhibitors Related | Taletrectinib | Amitriptyline | Larotrectinib sulfate | N-Acetyl-5-hydroxytryptamine | Larotrectinib | SP600125 | 7,8-Dihydroxyflavone | Amitriptyline hydrochloride | Tepotinib | GW 441756 | ALE-0540 | NSI-189 Phosphate |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Post-Translational Modification Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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Price |
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Suppliers |
Update time |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States